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(二合一)熱痛覺測量儀

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二合一熱痛覺測量儀包含足底痛覺測量儀和甩尾測痛儀:

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二合一熱痛覺測量儀包含足底痛覺測量儀和甩尾測痛儀

  • Plantar Test Hargreaves Method 足底痛覺測量儀

  • Tail Flick Test Analgesia Meter Apparatus 甩尾測痛儀


型號390型+33型 或 390G型+33型


足底痛覺實驗用于測試鎮(zhèn)痛藥物影響無束縛大鼠對外部熱刺激的反應(yīng)時間使用時先通過從爪下面的測試頭發(fā)出導向光將光源移到動物爪底通過反光鏡確定位置避免頻繁彎腰和低頭方便操作啟動加熱光束照射到動物爪底進行實驗。


足底熱測痛儀主要特點     


精確數(shù)字控制 時間精確度為0.01s

自動切斷保護功能

光束強度可調(diào)節(jié)步進量1

手工結(jié)束測試減少誤觸發(fā)

強制取消定時器功能

數(shù)字顯示功能

動物不需固定限制

加熱玻璃可選配

測試頭具有反光鏡輔助觀察

標準計算機打印口輸出

型號390 爪刺激痛覺測試儀

型號390G 爪刺激痛覺測試儀內(nèi)置熱玻璃


疼痛甩尾測試儀用于測試動物疼痛反應(yīng)時間和動物對鎮(zhèn)痛藥物的疼痛反應(yīng)極限。實驗過程中檢測到動物尾部甩動后內(nèi)置的計時器自動停止計時。


疼痛甩尾測試儀主要特點 

 

實時尾部溫度/觸發(fā)可選

觸發(fā)溫度設(shè)置功能

精確數(shù)字控制時間精確度為0.01

自動切斷保護功能

光束強度可調(diào)節(jié)步進量1

自動檢測活動反應(yīng)

強制取消定時器功能

數(shù)字顯示功能

標準計算機打印口輸出


The IITC Plantar Test Analgesia Meter for paw stimulation can be used on 12 mice, 6 rats and other animals (cats, rabbits) unrestrained when testing for narcotic drugs. Experiments are easy to perform, simply slide the test head under test subject, align the heat source via our exclusive guide light (idle state) by the attached, adjustable, angled mirror on test head to test subject and perform tests.


Start, stop and reset of tests is done by either the push button on test head, front panel controls or supplied footswitch.

With our exclusive “idle state” of the heat source one is assured of exact placement of the heat source. Tests are performed on the plantar surface by a focused, radiant heat light source. The light beam is focused to the top of the glass and creates a 4X6mm intense spot on the paw.


Our method of visible light is superior to the infrared light method, since a user will not always know exactly where/when the test will start, causing false starts and conditioning of animals. A built-in timer displays reaction time in .01 second increments.


The height of the glass is adjustable allowing the focal point of the light to be adjusted to stimulate other body parts if needed. A Humane cutoff timer is standard. The unit can be preset for a cutoff period, at the end of which the heat source shuts off automatically if the animal has not responded, avoiding tissue damage. Our test head does not emit , clicking or whining noises that cause preconditioning of animals prior to test as with other systems on the market.

Our exclusive heated glass option eliminates the glass acting as a heat sink. This feature will eliminate the reaction time of the animals to be altered due to the fact that they are placed on cold glass allowing the possibility of delayed response time to the applied heat source. Built-in heating elements in the glass which are digitally controlled for consistent temperatures. Temperature readout and adjustment from 30-40 degrees c. for the heated base is controlled on the heated base.


a                      Tail Temperature Option a Animal enclosure

a


Three individual, acrylic animal enclosures are supplied. Each enclosure allows for 2 rats/4 mice allowing testing of up to 6 rats/12mice total. Enclsoures have strong magnets to prevent animals from possible escape., individual lids, clear dividers in-between test subjects.

Tail Flick Test mode - the test head is attached to the electronic gear and the heat source now sits over a tail groove that has a sensor that detects the when the animal flicks it tail. System records and displays time and temperature of test. A humane cutoff timer that can be set by user, preventing tail tissue damage if test subject has not reacted within preset time.

TAIL TEMPERATURE OPTION (T)
Measurement of tail temperature at all times.

Trigger temperature is automatic at the start of every test.

This optional feature allows automatic preheating of the tail. To ensure experiment protocols to be precisely controlled and repeated. This feature allows the user to SET the tail temperature at start of each test is to be started at up to 75 degrees Celsius. Once that preset temperature is reached the test and the timer starts automatically and after the tail flicks the timer and light stop and the result is displayed. Readout will now show in repeatable sequence the start and end temperatures as well as test time. 
We recommend animals be restrained with one of the IITC restrainers.

This unit solves the problem associated with “tail temperature prior to and at the end of testing.”
See articleKJELL HOLE AND ARNE TJOLSENThe Tail-Flick Formalin Test in RodentsChanges in Skin Temperature as a Confounding Factor. 
Pain 53 (1993) pages. 247-254 Elsevier).

Features
Tail Temperature optional (T)
Precise Programmable digital control 
Humane cut-off feature, set by user 
Adjustable beam intensity in 1% increments 
Reaction is detected automatically 
(Tail Flick Test set-up) 
Manual override of all timer functions
All Functions and parameters entered via key-pad 
Heated glass option only from IITC
Footswitch - RS232 - Printer output (standard)



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… adverse developmental consequences produced by early brain injuries, especially in animal
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withdrawal test carried out using an Analgesia Meter apparatus (Mod 33, IITC, INC, USA …

  

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… The animals were used only once. Testing of tail flick was performed using an IITC Inc. Model
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… The thermal paw withdrawal test was carried out using an Analgesia Meter apparatus (Mod 33,
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Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice

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… paws of rats were tested individually using a thermal stimulus apparatus (model 33 Analgesia
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Consistent with many previous studies which have characterized afferent projections to …


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